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Search Results for " Fibroblast growth factor receptor "

ターゲット

72

阻害剤

7

天然化合物

83

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T9030 SU4984 FGFR , IGF-1R , PDGFR
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
T5466 Tyrosine kinase-IN-1 VEGFR , FGFR , FLT , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
T6996 SU 5402 SU5402 VEGFR , FGFR , PDGFR
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
T2642 PD173074 Apoptosis , EGFR , VEGFR , FGFR , IGF-1R , Src
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
T3466 FIIN-3 EGFR , FGFR
FIIN-3 is an irreversible inhibitor of FGFR.
T6082 SSR128129E SSR FGFR
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.
T1777 Nintedanib BIBF 1120,Intedanib VEGFR , FGFR , FLT , PDGFR , Src
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T2347 BLU9931 FGFR
BLU9931 is the first selective small molecule inhibitor of FGFR4.
T6836 FIIN-2 FGFR
FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.
T8976 PD-089828 EGFR , FGFR , PDGFR , Src
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...
T1948 AZD4547 VEGFR , FGFR
AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).
T7611 ODM-203 VEGFR , FGFR
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
T15185 Lucitanib E-3810 VEGFR , FGFR
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
TQ0256 FGFR4-IN-1 FGFR
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
T0520 Lenvatinib E7080 VEGFR , FGFR , c-RET , PDGFR , c-Kit
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (...
T2358 ENMD-2076 Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T3492 PD-166866 PD166866 FGFR , Autophagy
PD-166866 is a selective FGFR tyrosine kinase inhibitor.
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T3714 SUN11602 SUN 11602 ERK , FGFR
SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level...
T5473 ASP5878 ASP-5878 FGFR
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.
TQ0015 PRN1371 c-Fms , FGFR , CSF-1R
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
T16781 Rogaratinib BAY1163877 FGFR
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
T3274 S49076 FGFR , c-Met/HGFR , TAM Receptor
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.
TQ0228 Derazantinib ARQ-087 FGFR
Derazantinib (ARQ-087) (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
T2361 LY2874455 LY 2874455,LY-2874455 VEGFR , FGFR
LY2874455 has been used in trials studying the treatment of Advanced Cancer.
T5122 Alofanib RPT835 Apoptosis , FGFR
Alofanib (RPT835) is a selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect on FGF2-induced phosphorylation of FRS2a in KATO III cells (IC50 <10 nM). It has no direct effect on FGF2-dependent FGFR...
T4318 EOC317 ACTB-1003,ACTB1003,ACTB 1003 VEGFR , FGFR , Tie-2
EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).
T2372 Ponatinib AP24534 VEGFR , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Autophagy
Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively).
T8541 Lenvatinib mesylate E7080 (mesylate) VEGFR , FGFR , c-RET , PDGFR , c-Kit
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
T6184 Orantinib SU6668,TSU-68,NSC 702827 Apoptosis , VEGFR , FGFR , PDGFR
Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, A...
T12401 Pemigatinib INCB054828 FGFR
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
T2638 Gandotinib LY2784544 VEGFR , FGFR , FLT , JAK
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.
T3456 Fisogatinib BLU554,BLU 554,BLU-554 FGFR
Fisogatinib (BLU-554) is a potent inhibitor of fibroblast growth factor receptor 4 (FGFR4).
T5170 KHS101 hydrochloride FGFR , Microtubule Associated
KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.
T3726 Erdafitinib JNJ-42756493 Apoptosis , FGFR
Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.
T4235 Roblitinib FGF-401 FGFR
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...
T2609 Masitinib AB1010 Apoptosis , FAK , c-Fms , FGFR , Bcr-Abl , PDGFR , Src , c-Kit , Hck
Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet...
T1792 Regorafenib BAY 73-4506,Fluoro-Sorafenib Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.
T11279 FGFR1/DDR2 inhibitor 1 Discoidin Domain Receptor (DDR) , FGFR , Others
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
T6930 Pazopanib Hydrochloride GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, resp...
T5001 Nintedanib esylate Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120 VEGFR , FGFR , PDGFR
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β
T5044 Futibatinib TAS120,FGFR-IN-1 FGFR
Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.
T6289 Dovitinib TKI258,CHIR-258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...
T8544 Masitinib mesylate AB-1010 mesylate Apoptosis , FAK , FGFR , PDGFR , Src , c-Kit
Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;PDGFRα/β;LynB,respectively).
T8492 BO-264 Apoptosis , FGFR
BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).
T1975 Infigratinib BGJ-398,NVP-BGJ398 Apoptosis , FGFR
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
T6479 Dovitinib lactate hydrate Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...

Compounds

SU4984
T9030
Synonym:
Target: FGFR, IGF-1R, PDGFR
Tyrosine kinase-IN-1
T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
SU 5402
T6996
Synonym: SU5402
Target: VEGFR, FGFR, PDGFR
PD173074
T2642
Synonym:
Target: Apoptosis, EGFR, VEGFR, FGFR, IGF-1R, Src
FIIN-3
T3466
Synonym:
Target: EGFR, FGFR
SSR128129E
T6082
Synonym: SSR
Target: FGFR
Nintedanib
T1777
Synonym: BIBF 1120,Intedanib
Target: VEGFR, FGFR, FLT, PDGFR, Src
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
JK-P3
T4425
Synonym:
Target: VEGFR
BLU9931
T2347
Synonym:
Target: FGFR
FIIN-2
T6836
Synonym:
Target: FGFR
PD-089828
T8976
Synonym:
Target: EGFR, FGFR, PDGFR, Src
AZD4547
T1948
Synonym:
Target: VEGFR, FGFR
ODM-203
T7611
Synonym:
Target: VEGFR, FGFR
Lucitanib
T15185
Synonym: E-3810
Target: VEGFR, FGFR
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
FGFR4-IN-1
TQ0256
Synonym:
Target: FGFR
Lenvatinib
T0520
Synonym: E7080
Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit
ENMD-2076
T2358
Synonym:
Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase
PD-166866
T3492
Synonym: PD166866
Target: FGFR, Autophagy
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
SUN11602
T3714
Synonym: SUN 11602
Target: ERK, FGFR
ASP5878
T5473
Synonym: ASP-5878
Target: FGFR
PRN1371
TQ0015
Synonym:
Target: c-Fms, FGFR, CSF-1R
Rogaratinib
T16781
Synonym: BAY1163877
Target: FGFR
S49076
T3274
Synonym:
Target: FGFR, c-Met/HGFR, TAM Receptor
Derazantinib
TQ0228
Synonym: ARQ-087
Target: FGFR
LY2874455
T2361
Synonym: LY 2874455,LY-2874455
Target: VEGFR, FGFR
Alofanib
T5122
Synonym: RPT835
Target: Apoptosis, FGFR
EOC317
T4318
Synonym: ACTB-1003,ACTB1003,ACTB 1003
Target: VEGFR, FGFR, Tie-2
Ponatinib
T2372
Synonym: AP24534
Target: VEGFR, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Autophagy
Lenvatinib mesylate
T8541
Synonym: E7080 (mesylate)
Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit
Orantinib
T6184
Synonym: SU6668,TSU-68,NSC 702827
Target: Apoptosis, VEGFR, FGFR, PDGFR
Pemigatinib
T12401
Synonym: INCB054828
Target: FGFR
Gandotinib
T2638
Synonym: LY2784544
Target: VEGFR, FGFR, FLT, JAK
Fisogatinib
T3456
Synonym: BLU554,BLU 554,BLU-554
Target: FGFR
KHS101 hydrochloride
T5170
Synonym:
Target: FGFR, Microtubule Associated
Erdafitinib
T3726
Synonym: JNJ-42756493
Target: Apoptosis, FGFR
Roblitinib
T4235
Synonym: FGF-401
Target: FGFR
Masitinib
T2609
Synonym: AB1010
Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck
Regorafenib
T1792
Synonym: BAY 73-4506,Fluoro-Sorafenib
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy
FGFR1/DDR2 inhibitor 1
T11279
Synonym:
Target: Discoidin Domain Receptor (DDR), FGFR, Others
Pazopanib Hydrochloride
T6930
Synonym: GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala
Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Nintedanib esylate
T5001
Synonym: Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120
Target: VEGFR, FGFR, PDGFR
Futibatinib
T5044
Synonym: TAS120,FGFR-IN-1
Target: FGFR
Dovitinib
T6289
Synonym: TKI258,CHIR-258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Masitinib mesylate
T8544
Synonym: AB-1010 mesylate
Target: Apoptosis, FAK, FGFR, PDGFR, Src, c-Kit
BO-264
T8492
Synonym:
Target: Apoptosis, FGFR
Infigratinib
T1975
Synonym: BGJ-398,NVP-BGJ398
Target: Apoptosis, FGFR
Dovitinib lactate hydrate
T6479
Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
1 2
カタログ番号 製品名 別名 ターゲット
T19355 Heparan Sulfate FGFR , Wnt/beta-catenin , Endogenous Metabolite
Heparan Sulfate, a complex and linear polysaccharide, forms a component of glycoproteins called heparan sulfate proteoglycans, abundantly expressed on the cell surface and within the extracellular matrix.
T2215 Ferulic Acid Coniferic acid,Fumalic Acid FGFR , Endogenous Metabolite
Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a type of organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.It can be absorbed by the small intestine and excreted ...
T0724 Formononetin Biochanin B,Flavosil,Formononetol Apoptosis , FGFR
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
T2857 2,5-Dihydroxybenzoic acid 5-Hydroxysalicylic acid,Gentisic acid,Phloretate,Carboxyhydroquinone,Hydroquinonecarboxylic acid,Gentianic acid FGFR , Others , Endogenous Metabolite
2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.
T2S0007 Ferulic acid sodium Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate FGFR , Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite
Ferulic acid sodium (Sodium ferulic), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.
T3S0027 Picropodophyllotoxin AXL 1717,Picropodophyllin IGF-1R
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...
T40832 Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside
Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1). It exhibits IC50 values of 3.78 µM and 12.5 µM for FGFR1 and FGFR2, respectively.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02112 FGFR4 Protein, Human, Recombinant (His) Human HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-04165 FGFR3 Protein, Human, Recombinant (His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-03357 FGFR2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00423 FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-06034 FGFR1 Protein, Human, Recombinant (beta (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03683 FGFR4 Protein, Rhesus, Recombinant (His) Rhesus HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-02862 FGFR4 Protein, Rat, Recombinant (His) Rat HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-02635 FGFR4 Protein, Rat, Recombinant (hFc) Rat HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-03926 FGFR1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03350 FGFR1 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-03322 FGFR4 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-00257 FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-02853 FGFR3 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-00974 FGFR4 Protein, Mouse, Recombinant (His) Mouse HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-01019 FGFR4 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-06037 FGFR4 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPY-00806 FGFR4 Protein, Human, Recombinant (hFc) Human HEK293
Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid seque...
TMPJ-01312 TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His) Human Human Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 I...
TMPY-01360 FGFRL1 Protein, Mouse, Recombinant (His) Mouse HEK293
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserv...
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00475 FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00397 FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00847 FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) Mouse HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00400 FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPY-04200 FGFR3 Protein, Human, Recombinant (hFc) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-00389 FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-01208 FGFR3 Protein, Mouse, Recombinant (His) Mouse HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-00973 FGFR3 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-03389 FGFR2 Protein, Mouse, Recombinant (His) Mouse HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01781 FGFR1 Protein, Mouse, Recombinant (His) Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01782 FGFR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-04390 FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) Human Baculovirus-Insect Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-06321 FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00351 FGFR2 Protein, Human, Recombinant (beta IIIc, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01228 FGFR2 Protein, Human, Recombinant (aa 1-377, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-00403 FGF-7/KGF Protein, Human, Recombinant (His) Human E. coli
Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of st...
TMPY-00756 FGF-1 Protein, Human, Recombinant Human E. coli
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
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FGFR4 Protein, Human, Recombinant (His)
TMPY-02112
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (His)
TMPY-04165
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Species: Human
Expression System: HEK293
FGFR2 Protein, Mouse, Recombinant (hFc)
TMPY-03357
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00423
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
TMPY-06034
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293
FGFR4 Protein, Rhesus, Recombinant (His)
TMPY-03683
Species: Rhesus
Expression System: HEK293
FGFR4 Protein, Rat, Recombinant (His)
TMPY-02862
Species: Rat
Expression System: HEK293
FGFR4 Protein, Rat, Recombinant (hFc)
TMPY-02635
Species: Rat
Expression System: HEK293
FGFR1 Protein, Rhesus, Recombinant (His)
TMPY-03926
Species: Rhesus
Expression System: HEK293
FGFR1 Protein, Rhesus, Recombinant (hFc)
TMPY-03350
Species: Rhesus
Expression System: HEK293
FGFR4 Protein, Rhesus, Recombinant (hFc)
TMPY-03322
Species: Rhesus
Expression System: HEK293
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-00257
Species: Cynomolgus,Rhesus
Expression System: HEK293
FGFR3 Protein, Cynomolgus, Recombinant (hFc)
TMPY-02853
Species: Cynomolgus
Expression System: HEK293
FGFR4 Protein, Mouse, Recombinant (His)
TMPY-00974
Species: Mouse
Expression System: HEK293
FGFR4 Protein, Mouse, Recombinant (His & hFc)
TMPY-01019
Species: Mouse
Expression System: HEK293
FGFR4 Protein, Human, Recombinant (His), Biotinylated
TMPY-06037
Species: Human
Expression System: HEK293
FGFR4 Protein, Human, Recombinant (hFc)
TMPY-00806
Species: Human
Expression System: HEK293
TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)
TMPJ-01312
Species: Mouse
Expression System: Human Cells
FGFRL1 Protein, Human, Recombinant (His)
TMPJ-01224
Species: Human
Expression System: Human Cells
FGFRL1 Protein, Mouse, Recombinant (His)
TMPY-01360
Species: Mouse
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
TMPK-00399
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
TMPK-00475
Species: Cynomolgus
Expression System: HEK293
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00397
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
Species: Mouse
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00400
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (hFc)
TMPY-04200
Species: Human
Expression System: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, hFc)
TMPY-00389
Species: Human
Expression System: HEK293
FGFR3 Protein, Mouse, Recombinant (His)
TMPY-01208
Species: Mouse
Expression System: HEK293
FGFR3 Protein, Mouse, Recombinant (His & hFc)
TMPY-00973
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Mouse, Recombinant (His)
TMPY-01781
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Mouse, Recombinant (hFc)
TMPY-01782
Species: Mouse
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
TMPY-04390
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
TMPY-06321
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
TMPY-00351
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
TMPY-01228
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05761
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (hFc)
TMPY-05777
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His & GST)
TMPY-04371
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
TMPY-06035
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
TMPY-06033
Species: Human
Expression System: HEK293
FGF-7/KGF Protein, Human, Recombinant (His)
TMPY-00403
Species: Human
Expression System: E. coli
FGF-1 Protein, Human, Recombinant
TMPY-00756
Species: Human
Expression System: E. coli
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293